$5,000,000
Private Placement
Financial Advisor December 2016 
M&A Advisory
Financial Advisor December 2016$15,000,000
IPO
Sole Book-Running Manager December 2016$19,320,000
IPO
Joint Book-Running Manager December 2016$24,427,000
Follow-On
Sole Book-Running Manager December 2016$15,000,000
Registered Direct
Lead Placement Agent December 2016$10,001,000
Registered Direct
Financial Advisor December 2016$79,350,000
Follow-On
Co-Manager December 2016$9,680,000
Follow-On
Sole Book-Running Manager December 2016$1,500,000
Registered Direct
Sole Placement Agent December 2016$24,037,000
Follow-On
Financial Advisor December 2016$40,020,000
Follow-On
Co-Manager December 2016€37,600,000
PIPE
Lead Placement Agent December 2016€8,800,000
PIPE
Lead Placement Agent December 2016€57,500,000
PIPE
Lead Placement Agent December 2016$51,700,000
Follow-On
Co-Manager December 2016$18,515,000
Follow-On
Sole Manager December 2016$4,070,000
Registered Direct
Lead Placement Agent December 2016$15,594,000
Follow-On
Sole Book-Running Manager December 2016$82,747,000
Follow-On
Co-Manager December 2016$86,250,000
Follow-On
Co-Manager December 2016$763,000
Registered Direct
Financial Advisor December 2016$5,000,000
PIPE
Placement Agent December 2016AUD7,000,000
PIPE
Lead Placement Agent December 2016$40,259,000
Follow-On
Sole Manager December 2016
M&A Advisory
Financial Advisor November 2016$16,500,000
Follow-On
Lead Manager November 2016$12,500,000
Follow-On
Sole Book-Running Manager November 2016$4,001,000
Follow-On
Sole Book-Running Manager November 2016$80,300,000
Follow-On
Joint Book-Running Manager November 2016$150,000,000
Convertible Debt
Co-Manager November 2016$85,000,000
Private Placement
Sole Placement Agent October 2016$350,000,000
Documentation Agent
M&A Advisory
Financial Advisor October 2016$107,200,000
IPO
Co-Manager October 2016$136,364,000
IPO
Co-Manager October 2016$500,000
PIPE
Sole Placement Agent October 2016$7,560,000
Registered Direct
Placement Agent October 2016$6,600,000
Follow-On
Sole Book-Running Manager October 2016$10,010,000
Follow-On
Joint Book-Running Manager October 2016$201,825,000
Follow-On
Co-Manager October 2016$1,275,000
Follow-On
Sole Book-Running Manager October 2016$5,750,000
Follow-On
Sole Book-Running Manager October 2016$10,000,000
Follow-On
Financial Advisor October 2016
has acquired
M&A Advisory
Financial Advisor September 2016$22,500,000
PIPE
Sole Placement Agent September 2016$107,036,000
Follow-On
Lead Manager September 2016$9,890,000
Follow-On
Joint Book-Running Manager September 2016CAD11,468,000
Follow-On
Placement Agent September 2016$2,800,000
Follow-On
Sole Book-Running Manager September 2016$15,189,000
PIPE
Placement Agent September 2016$1,470,000
Registered Direct
Lead Placement Agent September 2016$287,500,000
Convertible Notes
Co-Manager September 2016$80,698,000
M&A Advisory
Financial Advisor August 2016$40,000,000
M&A Advisory
Financial Advisor August 2016$30,200,000
M&A Advisory
Financial Advisor August 2016$7,536,000
PIPE
Placement Agent August 2016$14,900,000
Follow-On
Financial Advisor August 2016$15,800,000
PIPE
Financial Advisor August 2016$284,625,000
Follow-On
Co-Manager August 2016$17,308,000
Follow-On
Co-Manager August 2016$5,875,000
Registered Direct
Financial Advisor August 2016$9,250,000
Registered Direct
Lead Manager August 2016$50,000,000
Follow-On
Co-Manager August 2016$4,274,000
Private Placement
Placement Agent July 2016
M&A Advisory
Financial Advisor July 2016$4,000,000
Registered Direct
Sole Placement Agent July 2016$5,000,000
Follow-On
Sole Book-Running Manager July 2016$42,708,000
M&A Advisory
Financial Advisor June 2016$17,100,000
M&A Advisory
Financial Advisor June 2016$67,200,000
M&A Advisory
Financial Advisor June 2016$11,500,000
Follow-On
Joint Book-Running Manager June 2016$49,915,000
Follow-On
Financial Advisor June 2016$23,975,000
Registered Direct
Financial Advisor June 2016$16,500,000
PIPE
Financial Advisor June 2016$1,918,000
Registered Direct
Lead Placement Agent June 2016$35,000,000
PIPE
Sole Placement Agent June 2016$5,200,000
Follow-On
Financial Advisor June 2016$5,000,000
Registered Direct
Lead Placement Agent June 2016$16,677,000
Follow-On
Joint Book-Running Manager June 2016$152,000,000
Convertible Senior Notes
Sole Placement Agent June 2016
has received an investment from
M&A Advisory
Financial Advisor May 2016
M&A Advisory
Financial Advisor May 2016$18,500,000
IPO
Joint Book-Running Manager May 2016$12,371,000
PIPE
Sole Placement Agent May 2016$9,229,000
Follow-On
Sole Book-Running Manager May 2016$50,000,000
Follow-On
Co-Manager May 2016$15,000,000
Private Placement
Sole Placement Agent May 2016$513,190,000
Follow-On
Sole Book-Running Manager May 2016$980,000
Registered Direct
Sole Placement Agent May 2016$1,080,000
PIPE
Financial Advisor May 2016$5,000,000
Registered Direct
Sole Placement Agent May 2016$16,754,000
Follow-On
Sole Book-Running Manager May 2016$8,000,000
Follow-On
Sole Book-Running Manager May 2016$25,395,000
PIPE
Placement Agent May 2016$20,000,000
Private Placement
Financial Advisor April 2016
has merged with
M&A Advisory
Financial Advisor April 2016$8,372,000
IPO
Sole Manager April 2016$5,000,000
Registered Direct
Financial Advisor April 2016$750,000
PIPE
Sole Placement Agent April 2016$15,000,000
PIPE
Sole Placement Agent April 2016$10,000,000
PIPE
Sole Placement Agent April 2016$1,277,000
Private Placement
Placement Agent March 2016$8,678,000
M&A Advisory
Financial Advisor March 2016CAD17,313,000
Follow-On
Placement Agent March 2016$3,342,000
Follow-On
Sole Book-Running Manager March 2016$43,700,000
Follow-On
Co-Manager March 2016$6,825,000
Follow-On
Joint Book-Running Manager March 2016$6,700,000
Registered Direct
Placement Agent March 2016$10,000,000
Follow-On
Sole Book-Running Manager March 2016$4,061,000
Registered Direct
Financial Advisor March 2016$12,075,000
Follow-On
Co-Manager March 2016$129,999,000
Follow-On
Co-Manager March 2016
M&A Advisory
Financial Advisor February 2016$8,320,000
M&A Advisory
Financial Advisor February 2016$3,557,000
Follow-On
Sole Placement Agent February 2016CAD12,706,000
Follow-On
Placement Agent February 2016$8,000,000
Follow-On
Sole Book-Running Manager February 2016
M&A Advisory
Financial Advisor January 2016$15,000,000
PIPE
Financial Advisor January 2016$21,750,000
Follow-On
Co-Manager January 2016$7,726,000
ATM Program
Sole Agent January 2016